| # | Children | Name | Born | Died | Father | Mother |
|---|
| 1 | | | | | King Henry II of France Henry of Valois, II | Janet Stewart |
| 2 | | | b. Apr 1577 | d. 02 Jun 1586 | King Henry II of France Henry of Valois, II | Janet Stewart |
| 3 | | | b. 1538 | d. 11 Jan 1619 | King Henry II of France Henry of Valois, II | Philippa of France |
| 4 | | | b. Abt 1557 | d. 14 Feb 1621 | King Henry II of France Henry of Valois, II | Nicole De Savigny |
| 5 | | | b. Abt 1545 | | King Henry II of France Henry of Valois, II | Unknown |
| 6 | | | b. 19 Jan 1544 | d. 5 Dec 1560 | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 7 | | | b. 02 Apr 1544 | d. 03 Oct 1568 | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 8 | | | b. Abt 1546 | | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 9 | | | b. 12 Nov 1547 | d. 20 Feb 1575 | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 10 | | | b. 3 Feb 1548 | d. 24 Oct 1550 | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 11 | Yes | | b. 27 Jun 1550 | d. 30 May 1574 | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 12 | | | b. 19 Sep 1551 | d. 2 Aug 1589 | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 13 | | | b. 15 May 1553 | d. 27 Mar 1615 | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 14 | | | b. 18 Mar 1554 | d. 10 Jun 1584 | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 15 | | | b. 24 Jun 1556 | d. 17 Aug 1556 | King Henry II of France Henry of Valois, II | Catherine De Medici |
| 16 | | | b. 24 Jun 1556 | d. 24 Jun 1556 | King Henry II of France Henry of Valois, II | Catherine De Medici |
1519 - 1559 (40 years)