Karl married Princess of Hesse-Darmstadt Luise Auguste on 03 Oct 1775 in Karlsruhe, Karlsruhe, Baden. Luise (daughter of Landgrave of Hesse-Darmstadt Ludwig, IX and Karoline Henriette Christine Birkenfeld) was born on 30 Jan 1757 in Berlin, Brandenburg, Prussia; died on 14 Feb 1830 in Weimar, Saxe-Weimar-Eisenach, Thuringia. [Group Sheet] [Family Chart]

1. Princess of Saxe Luise Auguste Amalie was born on 3 Feb 1779 in Weimar, S-W-Es, Thrn; died on 24 Mar 1784.
2. Princess of Saxe Daughter was born on 10 Sep 1781 in Weimar, S-W-Es, Thrn; died on 10 Sep 1781.
3. Grand Duke Saxe-Weimar-Eisenach Karl Friedrich was born on 21 Jan 1783 in Weimar, S-W-Es, Thrn; died on 26 Jun 1853 in Weimar, S-W-Es, Thrn.
4. Prince of Saxe _____ Saxe was born on 26 Feb 1785 in Weimar, S-W-Es, Thrn; died on 26 Feb 1785.
5. Princess of Saxe-Weimar-Eisenach Karoline Luise was born on 18 Jul 1786 in Wismar, Mecklenburg-Schwerin, Germany; died on 20 Jan 1816 in Ludwigslust, Mecklenburg-Schwerin, Germany.
6. Prince of Saxe _____ Saxe was born on 13 Apr 1789 in Weimar, S-W-Es, Thrn; died on 13 Apr 1789.
7. Duke of Saxe Weimar Karl Bernhard was born on 30 May 1792 in Weimar, Saxe-Weimar-Eisenbach, Thuringia; died on 31 Jul 1862 in Liebenstein, Saxe-Meningen, Thuringia.

Ernst + Princess of Brunswick-Wolfenbhuttel Anna Amalie. [Group Sheet] [Family Chart]