Karoline married Landgrave of Hesse-Kassel-Rumpenheim Friedrich on 02 Dec 1786 in Biebrich, Hessen-Nassau, Prussia. Friedrich (son of Prince of Prussia Augustus Wilhelm and Princess Luise Amalie Brunswick-Wolfenbhuttel, son of Landgrave of Hesse-Kassel Friedrich, II and Mary Hanover) was born on 11 Sep 1747 in Kassel, Hessen-Nassau, Prussia; was christened on 21 Sep 1747 in Kassel, Hessen-Nassau, Prussia; died on 20 May 1837 in Frankfurt Am Main, Hessen-Nassau, Prussia; was buried on 23 May 1837 in Rumpenheim, Starkenburg, Hessen-Darmstadt. [Group Sheet] [Family Chart]

1. Landgrave William Hesse-Kassel was born on 24 Dec 1787 in Schloss Biebrich, Hessen-Nassau, Prussia; was christened on 28 Dec 1787 in Schloss Biebrich, Hessen-Nassau, Prussia; died on 5 Sep 1867 in Kobenhavn, Denmark; was buried on 27 Sep 1867 in Rumpenheim Kirche, Starkenburg, Hesse-Darmstadt.
2. Prince of Hesse-Kassel-Rumpenheim Karl Friedrich was born on 8 Mar 1789 in Maastrict, Limburg, Netherlands; was christened on 15 Mar 1789 in Maastrict, Limburg, Netherlands; died on 10 Sep 1802.
3. Prince of Hesse-Kassel-Rumpenheim Friedrich Wilhelm was born on 25 Apr 1790 in Maastrict, Limburg, Netherlands; was christened on 2 May 1790 in Maastrict, Limburg, Netherlands; died on 25 Oct 1876.
4. Prince of Hesse-Kassel-Rumpenheim Ludwig Karl was born on 12 Nov 1791 in Schloss Biebrich, Hessen-Nassau, Prussia; was christened on 17 Nov 1791; died on 12 May 1800.
5. Prince of Hesse Georg Karl was born on 14 Jan 1793 in Maastrict, Limburg, Netherlands; was christened on 20 Jan 1793 in Maastrict, Limburg, Netherlands; died on 4 Mar 1881.
6. Princess of Hesse Luise Karoline Marie Friederike was born on 9 Apr 1794 in Maastricht, Limburgh, Netherlands; died on 16 Mar 1881.
7. Marie Wilhelmine Friederike Hesse-Darmstadt was born on 21 Jan 1796 in Castle Hanau, Hessen-Nassau, Prussia; was christened on 27 Jan 1796 in Castle Hanau, Hessen-Nassau, Prussia; died on 30 Dec 1880 in Neustrelitz, Mecklenburg, Germany; was buried on 04 Jan 1881 in Mirow, Mecklenburg-Strelitz, Germany.
8. Princess Augusta Hesse-Kassel was born on 25 Jul 1797 in Schloss, Rumpenheis, Starkenburg, Hesse-Darmstadt; was christened on 31 Jul 1797 in Rumpenheim, Starkenburg, Hesse-Darmstadt; died on 06 Apr 1889 in St. James's Palace, Westminster, London, England; was buried on 13 Apr 1889 in Kew, Surrey, England.

Karl married Karoline Leiningen-Dachsburg-Heidesheim on 16 Apr 1760 in Heidesheim, Pfalz, Bavaria. Karoline was born on 22 May 1734 in Heidesheim, Pfalz, Bavaria; died on 08 May 1810 in Frankfurt Am Main, Hessen-Nassau, Prussia. [Group Sheet] [Family Chart]