Louisa married Elector of Palentine Friedrich, IV on 12 Jun 1593 in Dillenburg, Hessen-Nassau, Prussia. Friedrich (son of Elector of Palatine Ludwig, VI and Princess of Hesse-Kassel Elisabeth) was born on 05 Mar 1574 in Bamberg, Oberfranken, Bavaria; died on 09 Sep 1610 in Heidelberg, Heidelberg, Baden-Württemberg, Germany; was buried in Heidelberg, Heidelberg, Baden-Württemberg, Germany. [Group Sheet] [Family Chart]

1. Princess of Palatine Luise Juliane was born on 16 Jul 1594 in Heidelberg, Heidelberg, Baden-Württemberg, Germany; died on 28 Apr 1640 in Meisenheim, Rheinland, Prussia; was buried in Stadtkirche, Meisenheim, Rheinland, Prussia.
2. Princess of Palatine Katharine Sofie was born on 10 Jun 1595 in Heidelberg, Heidelberg, Baden-Württemberg, Germany; died on 28 Jun 1626.
3. King of Bohemia Frederick, V was born in 1596 in Bohemia, Czech Republic; died in 1632; was buried in Frankenthal, Pfalz, Bavaria.
4. Elizabeth Charlotte Of Palatine was born in 1597 in Palatine, Germany; died in 1660.
5. Princess of Palatine Elisabeth Charlotte was born on 7 Nov 1597 in Neumarkt, Oberpfalz, Bavaria; died on 16 Apr 1660 in Krossen On Oder, Brandenburg, Prussia; was buried on 4 Sep 1660 in Cathedral, Berlin, Brandenburg, Prussia.
6. Princess of Palatine Anna Eleonore was born on 26 Dec 1598 in Heidelberg, Baden; died on 24 May 1600.
7. Prince of Palatine Ludwig Wilhelm was born on 5 Aug 1600 in Heidelberg, Baden; died on 30 Sep 1600.
8. Prince of Palatine Moritz Christian was born on 8 Sep 1601 in Heidelberg, Heidelberg, Baden-Württemberg, Germany; died on 18 Mar 1605.
9. Count Palatine of Simmern Ludwig Philipp was born on 23 Nov 1602 in Heidelberg, Baden; died on 6 Jan 1655 in Crossen, Schlesien, Prussia; was buried in Simmern, Rheinland, Prussia.